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Rare Colored Bulldogs and their Genetics

I am a former High School AP Chemistry/Biology teacher with a degree in biochemistry. I have tried to summarize the genetics behind the rare colored bulldogs we are producing at Olde South.

Geno=gene (deals with what the dogs actual genes look like), pheno (P is for picture, deals with what the dog physically looks like, the physical picture of the dog). You can also consider genotype is what is on the inside, phenotype is what is on the outside. There are several genetic locations (Loci) in which determine a dog’s color genetically. At each location, is a pair of genes (Alleles).

For Blue, the Loci, or location is called D for dilution. The possible alleles (or genes) at the D loci are “D” and “d”. Every dog is either “D-D”, “D-d”, or “d-d”. These are the genotypes. A genotype of “D-D” produces a pheontype of Non-dilute, or non-blue. The genotype “D-d” is what is typically called a “blue-carrier”. These dogs have a phenotype EXACTLY the same as “D-D”. They are NON-dilutes, and NON-blues. “D” is a dominant allele over “d” so only dogs which have a “d-d” genotype will have a blue or dilute phenotype. In other words, only “d-d” dogs are actually blue in color. Blue is a dilution which acts on black pigment as well as black colored hairs. Any pigment or hairs that would otherwise be black are diluted from black to blue on a “d-d” dog. This is what makes solid blue, blue brindle, blue fawn, blue pied, blue with tan points, blue masked fawn, blue sable fawn, and all other varieties of blue possible. D-d and d-d dogs can produce blue offspring. Any dog D-D, that is bred to a blue d-d, will produce an entire litter of D-d puppies, which are blue-carriers, but not blue. Each puppy inherits one gene from each parent.

The next Loci to talk about is K. At the K loci is where the determination is made for brindle or fawn. Possible alleles are K, Kbr, and k. K is dominant (solid black) kbr brindle and k fawn.  We can simplify this loci to a basic dominant-recessive relationship (similar to blue or chocolate) with “kbr” (brindle) being dominant over “k” (fawn or non-brindle). “kbr-kbr” and “kbr-k” would be brindle, while only “k-k” would be fawn (or non-brindle). A Homozygous (which just means two of the same gene) brindle “kbr-kbr” would always produce brindle pups. This would be beneficial if one is trying to produce brindle-colored pups, or detrimental if one is trying to produce non-brindles. If the dog has just one K gene for solid black they will only be black with no other coloration with the exception of white like a black lab. K masks all other possible secondary colors in the phenotype but they ca be carriers for the “point colors”.

The A loci is the one responsible for the different variations of fawn. Possible alleles are Ay, aw, at, and a. Ay is dominant (solid) fawn.  aw is for wild or the wolf-type grey color.  at is responsible for tan points (black and tans). Lastly, a, is recessive black.

A blue tri bulldog would have to be kk (no dominant black “K” or brindle), at at for the point colors, and have the dd recessive. All the recessive genes must occur in this combination. A blue tri is a very rare color combination and much higher in price because the chances of having a blue tri dog are very slim!! The Lilac is the most misunderstood. Lilac bulldogs are simply diluted chocolate. A lilac tri must be kk (non dominant black non bindle),  bb (brown causes black to be a brown or chocolate color), dd (dilution gene to get the light chocolate), or atat  (for the tan points producing lilac tri).  I believe all the recessive genes in this combination are very very unlikely so I strongly recommend a DNA test be done before purchase.

Chocolate works in a similar way to blue as it is recessive. At the chocolate loci, B (I say B for brown) exists the two alleles “B” and “b”. Bulldogs can either be “BB” or “Bb” (non-chocolate). For a dog to be chocolate they must have a “bb” genotype creating a chocolate phenotype. B is dominant to b so only those dogs with a “bb” genotype will express the chocolate color. Chocolate is similar to a dilution as it acts upon black pigment making it brown. So the genotype of a chocolate dog can be K,bb (self colored like a chocolate lab) or kk,atat,bb (chocolate tri), and finally kk,Ayat,bb (chocolate dog that is a point carrier).

The last loci to discuss is S, patches of white. This is where piebald markings come from. Alleles are S, si, sp, and sw. S is dominant for self-colored (can have white chest or toes – under 10 percent white). The si is for Irish spotting, which usually is white chest, lower legs, undersides, white collar, white blaze and can be 10-30 percent white. The sp allele is for the typical piebald, which is random spots of color can be 20-80 percent white and is usually non-symmetrical. The sw allele is for extreme white.

I would be happy to evaluate the possible genetic make up of your puppy based on my experience, education, and research. Let me know if I can help you understand the color genetics of the bulldog. I appreciate any comments and contributions on this issue.